BDBM593231 N-((1R,4R)-4-(((2-((4-(3-oxa-8- azabicyclo[3.2.1]octan-8- yl)phenyl)amino)-5- fluoropyrimidin-4- yl)oxy)methyl)cyclohexyl)-2,2,2- trifluoroacetamide::US11578061, Example 209

SMILES Fc1cnc(Nc2ccc(cc2)N2C3CCC2COC3)nc1OC[C@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F

InChI Key InChIKey=UAGOSPTZMIUKOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593231   

LigandPNGBDBM593231(N-((1R,4R)-4-(((2-((4-(3-oxa-8- azabicyclo[3.2.1]o...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent