BDBM593235 2,2,2-trifluoro-N-((1R,4R)-4-(((5- fluoro-2-((1-isopropyl-3-methoxy- 1H-pyrazol-4-yl)amino)pyrimidin- 4- yl)oxy)methyl)cyclohexyl) acetamide::US11578061, Example 213

SMILES COc1nn(cc1Nc1ncc(F)c(OC[C@H]2CC[C@@H](CC2)NC(=O)C(F)(F)F)n1)C(C)C

InChI Key InChIKey=MBSXXOKOSJXRIS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593235   

LigandPNGBDBM593235(2,2,2-trifluoro-N-((1R,4R)-4-(((5- fluoro-2-((1-is...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent