BDBM593247 4-(((5-fluoro-2-((1-(2- hydroxyethyl)-1H-pyrazol-4- yl)amino)pyrimidin-4- yl)oxy)methyl)cyclohexan-1-ol::US11578061, Example 225

SMILES OCCn1cc(Nc2ncc(F)c(OCC3CCC(O)CC3)n2)cn1

InChI Key InChIKey=LLRCRCYRIQDSPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593247   

LigandPNGBDBM593247(4-(((5-fluoro-2-((1-(2- hydroxyethyl)-1H-pyrazol-4...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent