BDBM593256 2-(4-((5-fluoro-4-(((1R,4R)-4- hydroxycyclohexyl)methoxy) pyrimidin- 2-yl)amino)-5-methyl-1H- pyrazol-1-yl)-2- methylpropanenitrile::US11578061, Example 234

SMILES Cc1c(Nc2ncc(F)c(OC[C@H]3CC[C@H](O)CC3)n2)cnn1C(C)(C)C#N

InChI Key InChIKey=KCIOHLLKRWBXMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593256   

LigandPNGBDBM593256(2-(4-((5-fluoro-4-(((1R,4R)-4- hydroxycyclohexyl)m...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent