BDBM593264 (1R,4R)-4-(((2-((5-chloro-1- (tetrahydro-2H-pyran-4-yl)-1H- pyrazol-4-yl)amino)-5- fluoropyrimidin-4- yl)oxy)methyl)cyclohexan-1-ol::US11578061, Example 242

SMILES O[C@H]1CC[C@H](COc2nc(Nc3cnn(C4CCOCC4)c3Cl)ncc2F)CC1

InChI Key InChIKey=QSCGSDIIMZGVDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593264   

LigandPNGBDBM593264((1R,4R)-4-(((2-((5-chloro-1- (tetrahydro-2H-pyran-...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent