BDBM593275 2-(4-((5-fluoro-4-((4-hydroxy-4- methylcyclohexyl)methoxy)pyrimidin- 2-yl)amino)-3-methyl-1H- pyrazol-1-yl)-2- methylpropanenitrile::US11578061, Example 253

SMILES Cc1nn(cc1Nc1ncc(F)c(OCC2CCC(C)(O)CC2)n1)C(C)(C)C#N

InChI Key InChIKey=UJEYUBBGXFGKCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593275   

LigandPNGBDBM593275(2-(4-((5-fluoro-4-((4-hydroxy-4- methylcyclohexyl)...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent