BDBM593278 4-(((5-fluoro-2-((1-isopropyl-1H- pyrazol-4-yl)amino)pyrimidin-4- yl)oxy)methyl)bicyclo[2.2.2]octan- 1-ol::US11578061, Example 256

SMILES CC(C)n1cc(Nc2ncc(F)c(OCC34CCC(O)(CC3)CC4)n2)cn1

InChI Key InChIKey=XTFXLUKCAJBRLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593278   

LigandPNGBDBM593278(4-(((5-fluoro-2-((1-isopropyl-1H- pyrazol-4-yl)ami...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent