BDBM593281 2-(4-((5-fluoro-4-(((1S,3R,4R)-3- fluoro-4- hydroxycyclohexyl)methoxy) pyrimidin- 2-yl)amino)-3-methyl-1H- pyrazol-1-yl)-2- methylpropanenitrile::US11578061, Example 259

SMILES Cc1nn(cc1Nc1ncc(F)c(OC[C@H]2CC[C@@H](O)[C@H](F)C2)n1)C(C)(C)C#N

InChI Key InChIKey=ZMDAKVQYBDRIOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593281   

LigandPNGBDBM593281(2-(4-((5-fluoro-4-(((1S,3R,4R)-3- fluoro-4- hydrox...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent