BDBM593293 4-(((5-fluoro-2-((4- morpholinophenyl)amino)pyrimidin- 4-yl)oxy)methyl)cyclohexane-1- carbonitrile::US11578061, Example 272

SMILES Fc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1OCC1CCC(CC1)C#N

InChI Key InChIKey=REBNGOAAAYDBLH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593293   

LigandPNGBDBM593293(4-(((5-fluoro-2-((4- morpholinophenyl)amino)pyrimi...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent