BDBM593294 4-(((2-((4-((2S,6R)-2,6- dimethylmorpholino)phenyl)amino)- 5-fluoropyrimidin-4- yl)oxy)methyl)cyclohexane-1- carbonitrile::US11578061, Example 273

SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(Nc2ncc(F)c(OCC3CCC(CC3)C#N)n2)cc1

InChI Key InChIKey=APRMIQZUWAYDEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593294   

LigandPNGBDBM593294(4-(((2-((4-((2S,6R)-2,6- dimethylmorpholino)phenyl...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent