BDBM593295 4-(((2-((1-(2-cyanopropan-2-yl)-3- methyl-1H-pyrazol-4-yl)amino)-5- fluoropyrimidin-4- yl)oxy)methyl)cyclohexane-1- carbonitrile::US11578061, Example 274

SMILES Cc1nn(cc1Nc1ncc(F)c(OCC2CCC(CC2)C#N)n1)C(C)(C)C#N

InChI Key InChIKey=NWGPUSCSDWVTSI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593295   

LigandPNGBDBM593295(4-(((2-((1-(2-cyanopropan-2-yl)-3- methyl-1H-pyraz...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent