BDBM593298 2-(4-((4-((4- ethoxycyclohexyl)methoxy)-5- fluoropyrimidin-2-yl)amino)-3- methyl-1H-pyrazol-1-yl)-2- methylpropanenitrile::US11578061, Example 277

SMILES CCOC1CCC(COc2nc(Nc3cn(nc3C)C(C)(C)C#N)ncc2F)CC1

InChI Key InChIKey=OPEGYILDMXNSBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593298   

LigandPNGBDBM593298(2-(4-((4-((4- ethoxycyclohexyl)methoxy)-5- fluorop...)
Affinity DataIC50: 50nMAssay Description:LRRKtide substrate (peptide sequence RLGRDKYKTLRQIRQ, derived from human ezrin [amino acids 561-573], moesin [amino acids 539-553] and radixin [amino...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent