BDBM593405 N-(5-(difluoromethoxy)pyridin-3-yl)-N-((5- (5-(difluoromethyl)-1,3,4-oxadiazol-2- yl)thiazol-2-yl)methyl)ethanesulfonamide::US11578066, Compound I-257::US11578066, Compound I-96::US20230381148, Compound I-96

SMILES CCS(=O)(=O)N(Cc1ncc(s1)-c1nnc(o1)C(F)F)c1cncc(OC(F)F)c1

InChI Key InChIKey=WELFILVCSUDSIM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 593405   

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593405(N-(5-(difluoromethoxy)pyridin-3-yl)-N-((5- (5-(di...)
Affinity DataIC50:  10nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593405(N-(5-(difluoromethoxy)pyridin-3-yl)-N-((5- (5-(di...)
Affinity DataIC50:  231nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM593405(N-(5-(difluoromethoxy)pyridin-3-yl)-N-((5- (5-(di...)
Affinity DataIC50:  10nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent