BDBM593487 N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-1,3-thiazol-2-yl}methyl)-2-{3-oxa-6- azabicyclo[3.1.1]heptan-6-yl}-N-(pyridin-3- yl)ethane-1-sulfonamide::US11578066, Compound I-179::US20230381148, Compound I-179

SMILES FC(F)c1nnc(o1)-c1cnc(CN(c2cccnc2)S(=O)(=O)CCN2C3CC2COC3)s1

InChI Key InChIKey=KUSCFDBPAQGFJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 593487   

TargetHistone deacetylase 6(Homo sapiens (Human))
Tenaya Therapeutics

US Patent
LigandPNGBDBM593487(N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-...)
Affinity DataIC50:  13nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Tenaya Therapeutics

US Patent
LigandPNGBDBM593487(N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-...)
Affinity DataIC50:  13nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent