BDBM593487 N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-1,3-thiazol-2-yl}methyl)-2-{3-oxa-6- azabicyclo[3.1.1]heptan-6-yl}-N-(pyridin-3- yl)ethane-1-sulfonamide::US11578066, Compound I-179::US20230381148, Compound I-179
SMILES FC(F)c1nnc(o1)-c1cnc(CN(c2cccnc2)S(=O)(=O)CCN2C3CC2COC3)s1
InChI Key InChIKey=KUSCFDBPAQGFJW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 593487
Affinity DataIC50: 13nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair