BDBM593685 5-benzyl-N-(2-oxo-8-(7-oxa-2-azaspiro[3.5]nonan-2-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-1H-1,2,4-triazole-3-carboxamide::US11578078, Compound I-11

SMILES O=C(NC1CCc2ccc(cc2NC1=O)N1CC2(C1)CCOCC2)c1n[nH]c(Cc2ccccc2)n1

InChI Key InChIKey=UCHKGYVLTVWSKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 593685   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM593685(5-benzyl-N-(2-oxo-8-(7-oxa-2-azaspiro[3.5]nonan-2-...)
Affinity DataIC50: 414nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent