BDBM594837 US11584755, Example 126

SMILES COc1ccc(Cn2cc(Cn3c4ccsc4c(C(O)=O)c(O)c3=O)cn2)cc1

InChI Key InChIKey=XZAPMAPFDRHBFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 594837   

TargetFlap endonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594837(US11584755, Example 126)
Affinity DataIC50: 200nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetDNA excision repair protein ERCC-5(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594837(US11584755, Example 126)
Affinity DataIC50: 6.13E+3nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetExonuclease 1(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM594837(US11584755, Example 126)
Affinity DataIC50: 6.13E+3nMAssay Description:FEN1, EXO1 or XPG enzyme was incubated with compound or vehicle (DMSO) and the FAM-labeled DNA oligomer substrate in a microtiter plate. The stop buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent