BDBM594885 US11584756, Compound 4::US11584756, Example S-4

SMILES CCS(=O)(=O)Nc1ccc(Oc2c(C)cccc2C)c(c1)-c1cn(C)c(=O)c2sc(cc12)-c1nnc(C)o1

InChI Key InChIKey=UPMNAISUOZSEIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594885   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594885(US11584756, Example S-4 | US11584756, Compound 4)
Affinity DataIC50: 6nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594885(US11584756, Example S-4 | US11584756, Compound 4)
Affinity DataIC50: 197nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent