BDBM594889 US11584756, Compound 8::US11584756, Example S-8

SMILES Cc1noc(n1)-c1cc2c(cn(C)c(=O)c2s1)-c1cc(ccc1Oc1ccc(F)cc1F)C(C)(C)O

InChI Key InChIKey=ZBCGLWKWOIUYDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594889   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594889(US11584756, Example S-8 | US11584756, Compound 8)
Affinity DataIC50: 74nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594889(US11584756, Example S-8 | US11584756, Compound 8)
Affinity DataIC50: 94nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent