BDBM594894 US11584756, Compound 23::US11584756, Example S-13

SMILES Cn1cc(-c2cc(ccc2Oc2ccc(F)cc2F)C(C)(C)O)c2cc(sc2c1=O)C(=O)N1CCCC(F)(F)C1

InChI Key InChIKey=ZYJUUHXHIRNCSW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594894   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594894(US11584756, Example S-13 | US11584756, Compound 23)
Affinity DataIC50: 18nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594894(US11584756, Example S-13 | US11584756, Compound 23)
Affinity DataIC50: 1.12E+3nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent