BDBM594895 US11584756, Compound 10::US11584756, Example S-14

SMILES CCS(=O)(=O)Nc1ccc(Oc2c(C)cc(F)cc2C)c(c1)-c1cn(C)c(=O)c2sc(cc12)-c1nnc(C)o1

InChI Key InChIKey=FBAVLHWMTHLEAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594895   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594895(US11584756, Example S-14 | US11584756, Compound 10)
Affinity DataIC50: 3.40nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594895(US11584756, Example S-14 | US11584756, Compound 10)
Affinity DataIC50: 111nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent