BDBM594899 US11584756, Compound 148::US11584756, Example S-18

SMILES CCNC(=O)c1cc2c(cn(C)c(=O)c2s1)-c1cc(ccc1Oc1c(C)cc(F)cc1C)C(C)=C

InChI Key InChIKey=KICKGYHCZNJGTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594899   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594899(US11584756, Example S-18 | US11584756, Compound 14...)
Affinity DataIC50: 103nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594899(US11584756, Example S-18 | US11584756, Compound 14...)
Affinity DataIC50: 1.00E+4nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent