BDBM594910 US11584756, Compound 12::US11584756, Example S-29

SMILES Cc1nnc(o1)-c1cc2c(cn(C)c(=O)c2s1)-c1cc(ccc1Oc1ccc(F)cc1F)C(C)(C)O

InChI Key InChIKey=XOHKXICWLHQHMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594910   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594910(US11584756, Example S-29 | US11584756, Compound 12)
Affinity DataIC50: 12.5nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594910(US11584756, Example S-29 | US11584756, Compound 12)
Affinity DataIC50: 17nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent