BDBM594911 US11584756, Compound 159::US11584756, Example S-30

SMILES CCNC(=O)c1cc2c(s1)c(cn(C)c2=O)-c1cc(ccc1Oc1ccc(F)cc1F)C(C)(C)O

InChI Key InChIKey=TXGATJPEZFMNDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 594911   

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594911(US11584756, Example S-30 | US11584756, Compound 15...)
Affinity DataIC50: 1.70nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Nuvation Bio

US Patent
LigandPNGBDBM594911(US11584756, Example S-30 | US11584756, Compound 15...)
Affinity DataIC50: 18nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
US Patent