BDBM595618 US11591326, Compound 29a

SMILES Cn1cc(Nc2ccc3OCCN(C[C@H](O)CN4CCc5ccccc5C4)C(=O)c3c2)cn1

InChI Key InChIKey=FQCFUAUPXCLTQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595618   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandPNGBDBM595618(US11591326, Compound 29a)
Affinity DataIC50: 8.40nMAssay Description:General Procedure for PRMT5/MEP50 AlphaLISA Enzyme Inhibitory Assays: Assays were performed in the buffer consisting of 50 mM Tris, pH 8.5, 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent