BDBM595626 US11591326, Compound 34

SMILES CC1(C)CN(CC(O)CN2CCc3ccccc3C2)C(=O)c2cc(Nc3ccnnc3)ccc12

InChI Key InChIKey=HZNVSAYIDXARDP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 595626   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandPNGBDBM595626(US11591326, Compound 34)
Affinity DataIC50: 15.7nMAssay Description:General Procedure for PRMT5/MEP50 AlphaLISA Enzyme Inhibitory Assays: Assays were performed in the buffer consisting of 50 mM Tris, pH 8.5, 5 mM MgCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent