BDBM596365 2-(ethyl(2-ethyl-5-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl) piperazin-1-yl)-7-methyl-2H-pyrazolo[4,3-b]pyridin-3-yl)amino)-4-(4-fluorophenyl) thiazole-5-carbonitrile::US11591342, Compound S-0124

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1n(CC)nc2c(C)cc(nc12)N1CCN(CC(=O)N2CC(O)C2)CC1

InChI Key InChIKey=DIABSSXLGAQKDJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596365   

TargetAutotaxin(Human)
Suzhou Sinovent Pharmaceuticals

US Patent
LigandPNGBDBM596365(2-(ethyl(2-ethyl-5-(4-(2-(3-hydroxyazetidin-1-yl)-...)
Affinity DataIC50: 24nMAssay Description:Preparation and Treatment. Stock Solution Preparation. A 10 mM DMSO stock solution was formulated for each compound. A 30 mM DMSO stock solution was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent