BDBM596371 2-((2-ethyl-7-fluoro-5-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-2-(trifluoromethyl)piperazin-1-yl)-2H-indazol-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile::US11591342, Compound S-0131B

SMILES CCn1nc2c(F)cc(cc2c1N(C)c1nc(c(s1)C#N)-c1ccc(F)cc1)N1CCN(CC(=O)N2CC(O)C2)C[C@@H]1C(F)(F)F

InChI Key InChIKey=WJUTUWATTRHERW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596371   

TargetAutotaxin(Human)
Suzhou Sinovent Pharmaceuticals

US Patent
LigandPNGBDBM596371(2-((2-ethyl-7-fluoro-5-(4-(2-(3-hydroxyazetidin-1-...)
Affinity DataIC50: 36nMAssay Description:Preparation and Treatment. Stock Solution Preparation. A 10 mM DMSO stock solution was formulated for each compound. A 30 mM DMSO stock solution was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent