BDBM596374 (R)-2-(ethyl(2-ethyl-7-fluoro-5-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)piperazin-1-yl)-2H-indazol-3-yl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile::US11591342, Compound S-0135A

SMILES CCN(c1nc(c(s1)C#N)-c1ccc(F)cc1)c1n(CC)nc2c(F)cc(cc12)N1CCN(CC(=O)N2CC(O)C2)[C@H](C1)C(F)(F)F

InChI Key InChIKey=AOZAPVWPFMPQGM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 596374   

TargetAutotaxin(Human)
Suzhou Sinovent Pharmaceuticals

US Patent
LigandPNGBDBM596374((R)-2-(ethyl(2-ethyl-7-fluoro-5-(4-(2-(3-hydroxyaz...)
Affinity DataIC50: 132nMAssay Description:Preparation and Treatment. Stock Solution Preparation. A 10 mM DMSO stock solution was formulated for each compound. A 30 mM DMSO stock solution was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2023
Entry Details
US Patent