BDBM597884 US11608347, Example 21::[(7R,9aR)-7-(4- chlorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]-(7-chloro-2- methylsulfanyl- [1,3]thiazolo[5,4-b]pyridin- 6-yl)methanone

SMILES CSc1nc2c(Cl)c(cnc2s1)C(=O)N1CCN2C[C@H](CC[C@@H]2C1)c1ccc(Cl)cc1

InChI Key InChIKey=WUCFWUDTMOKTJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597884   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597884(US11608347, Example 21 | [(7R,9aR)-7-(4- chlorophe...)
Affinity DataIC50: 130nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent