BDBM597929 US11608347, Example 57::[(7R,9aR)-7-(4- chlorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]-[2-chloro-3- [(E)-2- cyclopropylethenyl]phenyl] methanone

SMILES Clc1ccc(cc1)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1cccc(\C=C\C2CC2)c1Cl

InChI Key InChIKey=KNCIAZSZCYPUOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597929   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597929(US11608347, Example 57 | [(7R,9aR)-7-(4- chlorophe...)
Affinity DataIC50: 61.3nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent