BDBM597931 (4-chloro-1H-pyrazolo[3,4- b]pyridin-5-yl)-[rac- (7R,9aR)-7-(3-chloro-4- fluorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 59::US11608347, Example 59-A

SMILES Fc1ccc(cc1Cl)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1cnc2[nH]ncc2c1Cl

InChI Key InChIKey=RMKUIEPKPVXWFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597931   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597931(US11608347, Example 59 | US11608347, Example 59-A ...)
Affinity DataIC50: 31nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597931(US11608347, Example 59 | US11608347, Example 59-A ...)
Affinity DataIC50: 89.5nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent