BDBM597934 (3-methyl-1H-indazol-5-yl)- [rac-(7R,9aR)-7-(3-chloro-4- fluorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 60::US11608347, Example 60-B

SMILES Cc1n[nH]c2ccc(cc12)C(=O)N1CCN2C[C@H](CC[C@@H]2C1)c1ccc(F)c(Cl)c1

InChI Key InChIKey=DYFHPYGTARBCKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597934   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597934(US11608347, Example 60 | US11608347, Example 60-B ...)
Affinity DataIC50: 90.1nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597934(US11608347, Example 60 | US11608347, Example 60-B ...)
Affinity DataIC50: 111nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent