BDBM597950 US11608347, Example 66::US11608347, Example 66-B::[2-chloro-3- (difluoromethoxy)phenyl]- [rac-(7R,9aR)-7-(3-chloro-4- fluorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]methanone

SMILES FC(F)Oc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(F)c(Cl)c2)c1Cl

InChI Key InChIKey=AYCOZPUFBCWXBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597950   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597950(US11608347, Example 66 | [2-chloro-3- (difluoromet...)
Affinity DataIC50: 13nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597950(US11608347, Example 66 | [2-chloro-3- (difluoromet...)
Affinity DataIC50: 26nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent