BDBM597955 (6-amino-4-chloropyridin-3- yl)-[rac-(7R,9aR)-7-(3- chloro-4-fluorophenyl)- 1,3,4,6,7,8,9,9a- octahydropyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 69

SMILES Nc1cc(Cl)c(cn1)C(=O)N1CCN2C[C@H](CC[C@@H]2C1)c1ccc(F)c(Cl)c1

InChI Key InChIKey=JRSHHXBEWHPONB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597955   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597955(US11608347, Example 69 | (6-amino-4-chloropyridin-...)
Affinity DataIC50: 73.1nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent