BDBM597957 (4-chloro-3-methyl-1H- indazol-5-yl)-[rac-(7R,9aS)- 7-(4-chlorophenyl)-7- hydroxy-3,4,6,8,9,9a- hexahydro-1H-pyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 71::US11608347, Example 71-A

SMILES Cc1n[nH]c2ccc(C(=O)N3CCN4C[C@](O)(CC[C@@H]4C3)c3ccc(Cl)cc3)c(Cl)c12

InChI Key InChIKey=KIPCARFHUJDZED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597957   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597957(US11608347, Example 71 | US11608347, Example 71-A ...)
Affinity DataIC50: 30.1nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597957(US11608347, Example 71 | US11608347, Example 71-A ...)
Affinity DataIC50: 38.2nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent