BDBM597961 US11608347, Example 71-B::[(7R,9aS)-7-(4- chlorophenyl)-7-hydroxy- 3,4,6,8,9,9a-hexahydro-1H- pyrido[1,2-a]pyrazin-2-yl]- (4-chloro-3-methyl-1H- indazol-5-yl)methanone

SMILES Cc1n[nH]c2ccc(C(=O)N3CCN4C[C@@](O)(CC[C@H]4C3)c3ccc(Cl)cc3)c(Cl)c12

InChI Key InChIKey=KIPCARFHUJDZED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597961   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597961(US11608347, Example 71-B | [(7R,9aS)-7-(4- chlorop...)
Affinity DataIC50: 99.5nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent