BDBM597969 (2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-chlorophenyl)- 7-hydroxy-3,4,6,8,9,9a- hexahydro-1H-pyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 73::US11608347, Example 73-A

SMILES COc1cccc(C(=O)N2CCN3C[C@](O)(CC[C@@H]3C2)c2ccc(Cl)cc2)c1Cl

InChI Key InChIKey=ZRYKFMWQAHFWJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 597969   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597969((2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-ch...)
Affinity DataIC50: 7.20nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597969((2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-ch...)
Affinity DataIC50: 18.5nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent