BDBM597971 US11608347, Example 73-B::[(7R,9aS)-7-(4- chlorophenyl)-7-hydroxy- 3,4,6,8,9,9a-hexahydro-1H- pyrido[1,2-a]pyrazin-2-yl]- (2-chloro-3- methoxyphenyl)methanone

SMILES COc1cccc(C(=O)N2CCN3C[C@@](O)(CC[C@H]3C2)c2ccc(Cl)cc2)c1Cl

InChI Key InChIKey=ZRYKFMWQAHFWJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597971   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597971(US11608347, Example 73-B | [(7R,9aS)-7-(4- chlorop...)
Affinity DataIC50: 156nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2023
Entry Details
US Patent