BDBM597975 US11608347, Example 77::[2-chloro-3-(2-oxa-6- azaspiro[3.3]heptan-6- yl)phenyl]-[rac-(7R,9aS)-7- (4-chlorophenyl)-7-hydroxy- 3,4,6,8,9,9a-hexahydro-1H- pyrido[1,2-a]pyrazin-2- yl]methanone

SMILES O[C@@]1(CC[C@@H]2CN(CCN2C1)C(=O)c1cccc(N2CC3(COC3)C2)c1Cl)c1ccc(Cl)cc1

InChI Key InChIKey=NISJSXPVUNPGRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597975   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597975(US11608347, Example 77 | [2-chloro-3-(2-oxa-6- aza...)
Affinity DataIC50: 39.7nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent