BDBM597979 (2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-chlorophenyl)- 7-methoxy-3,4,6,8,9,9a- hexahydro-1H-pyrido[1,2- a]pyrazin-2-yl]methanone::US11608347, Example 81

SMILES COc1cccc(C(=O)N2CCN3C[C@@](CC[C@@H]3C2)(OC)c2ccc(Cl)cc2)c1Cl

InChI Key InChIKey=JQPCMAAWCAVKHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 597979   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM597979(US11608347, Example 81 | (2-chloro-3- methoxypheny...)
Affinity DataIC50: 42.5nMAssay Description:In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...More data for this Ligand-Target Pair
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Date in BDB:
5/5/2023
Entry Details
US Patent