BDBM598685 US11613532, Example A6-1-2-1::rel-2-((3R,4R)-4-(((6-(((1,1- Difluorospiro[2.5]octan-6- yl)methyl)(ethyl)amino)-5- fluoropyrimidin-4-yl)amino)methyl)-3- hydroxypiperidin-l-yl)acetamide 1st eluting isomer

SMILES CCN(C[C@H]1CC[C@]2(CC2(F)F)CC1)c1ncnc(NC[C@@H]2CCN(CC(N)=O)C[C@H]2O)c1F

InChI Key InChIKey=NGJRFRDZPXUSOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598685   

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598685(US11613532, Example A6-1-2-1 | rel-2-((3R,4R)-4-((...)
Affinity DataIC50: 49nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent