BDBM598690 2-((3R*,4R*)-4-(((6- (cyclopropyl(((1r,4R)-4- (trifluoromethyl)cyclohexyl)methyl) amino)-5-fluoropyrimidin-4- yl)amino)methyl)-3-hydroxypiperidin- 1-yl)acetamide 1st eluting isomer::US11613532, Example A6-4-1

SMILES NC(=O)CN1CC[C@@H](CNc2ncnc(N(C[C@H]3CC[C@@H](CC3)C(F)(F)F)C3CC3)c2F)[C@H](O)C1

InChI Key InChIKey=QTPZEDSPYKGFRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598690   

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598690(US11613532, Example A6-4-1 | 2-((3R*,4R*)-4-(((6- ...)
Affinity DataIC50: 31nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
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Date in BDB:
5/10/2023
Entry Details
US Patent