BDBM598693 US11613532, Example A6-6-1::US11613532, Example A6-6-2::rel-2-((3R,4R)-4-(((6-(((2- oxaspiro[3.5]nonan-7- yl)methyl)(ethyl)amino)-5- fluoropyrimidin-4-yl)amino)methyl)-3- hydroxypiperidin-l-yl)acetamide 1st eluting isomer

SMILES CCN(CC1CC[C@]2(COC2)CC1)c1ncnc(NC[C@@H]2CCN(CC(N)=O)C[C@H]2O)c1F

InChI Key InChIKey=DQUKFCITXZXERP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 598693   

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598693(rel-2-((3R,4R)-4-(((6-(((2- oxaspiro[3.5]nonan-7- ...)
Affinity DataIC50: 690nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598693(rel-2-((3R,4R)-4-(((6-(((2- oxaspiro[3.5]nonan-7- ...)
Affinity DataIC50: 980nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent