BDBM598697 2-(4-(((5-fluoro-6-((3S)-3-(4- (trifluoromethyl)cyclohexyl)morpholino) pyrimidin-4- yl)amino)methyl)piperidin-1- yl)acetamide 2nd eluting isomer::US11613532, Example A6-8-2

SMILES NC(=O)CN1CCC(CNc2ncnc(N3CCOC[C@@H]3C3CC[C@@H](CC3)C(F)(F)F)c2F)CC1

InChI Key InChIKey=XMBGNLRWGCIDED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598697   

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598697(US11613532, Example A6-8-2 | 2-(4-(((5-fluoro-6-((...)
Affinity DataIC50: 480nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent