BDBM598700 2-((3R*,4R*)-4-((4-(ethyl(((1r,4R)-4- (trifluoromethyl)cyclohexyl)methyl) amino)-7H-pyrrolo[2,3-d]pyrimidin-7- yl)methyl)-3,4-dihydroxypiperidin-1- yl)acetamide 1st eluting isomer::US11613532, Example BD-5-1-1

SMILES CCN(C[C@H]1CC[C@@H](CC1)C(F)(F)F)c1ncnc2n(CC3(O)CCN(CC(N)=O)C[C@H]3O)ccc12

InChI Key InChIKey=KSAQLNORIHJLNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598700   

TargetNuclear receptor ROR-gamma(Human)
Nuevolution

US Patent
LigandPNGBDBM598700(US11613532, Example BD-5-1-1 | 2-((3R*,4R*)-4-((4-...)
Affinity DataIC50: 3.30nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent