BDBM598768 (1S,10R,13R) N-[(2,4-difluorophenyl)methyl]-10-(fluoromethyl)-6-hydroxy-13-methyl-5,8-dioxo-1,2,9-triazatricyclo[7.4.1.02,7]tetradeca-3,6,11-triene-4-carboxamide::US11613546, Example C49a

SMILES C[C@@H]1C=C[C@H](CF)[N@@]2CN1n1cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c1C2=O

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 598768   

TargetEnvelope glycoprotein gp160(HIV-1)
Gilead Sciences

US Patent
LigandPNGBDBM598768(US11613546, Example C49a | (1S,10R,13R) N-[(2,4-di...)
Affinity DataEC50:  1.20nMAssay Description:To quantify the amount of protein binding to human serum, compounds were serially diluted (1:3) in DMSO and acoustically transferred onto 384-well as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2023
Entry Details
US Patent