BDBM599198 5-[4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1,2,4]triazin-7-yl]- N-[(3R,4S)-4-fluoro-1-(3,3,3- trifluoro-2,2-dimethylpropanoyl) pyrrolidin-3-yl]-2-methoxy- pyridine-3-carboxamide, TFA::US11618753, Example 337

SMILES COc1ncc(cc1C(=O)N([C@@H]1CN(C[C@@H]1F)C(=O)C(C)(C)C(F)(F)F)C(=O)C(F)(F)F)-c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=AFDLPHBXVFLGNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 599198   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM599198(US11618753, Example 337 | 5-[4-amino-5-(trifluorom...)
Affinity DataIC50: 1.20E+3nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPK1(1-324) in FRET Buffer (20 mM HEP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent