BDBM600482 US11623923, Example 4

SMILES Nc1nccc(Oc2ccc(NC(=O)c3c[nH]c(=O)n(-c4ccc(F)cc4)c3=O)cc2F)c1Cl

InChI Key InChIKey=WCKQZMCXHJVIQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600482   

TargetHepatocyte growth factor receptor(Human)
Medshine Discovery

US Patent
LigandPNGBDBM600482(US11623923, Example 4)
Affinity DataIC50: 2.89nMAssay Description:Reagents and Materials:Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2023
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Medshine Discovery

US Patent
LigandPNGBDBM600482(US11623923, Example 4)
Affinity DataIC50: 17.7nMAssay Description:Reagents and Materials:Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2023
Entry Details
US Patent