BDBM600491 US11623923, Example 15

SMILES OC(Nc1cc(Oc2ccc(NC(=O)c3cn(CC4CC4)c(=O)n(-c4ccc(F)cc4)c3=O)cc2F)ccn1)N1CCC(O)CC1

InChI Key InChIKey=DAOGGCDCTXWDAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 600491   

TargetTyrosine-protein kinase receptor UFO(Human)
Medshine Discovery

US Patent
LigandPNGBDBM600491(US11623923, Example 15)
Affinity DataIC50: 3.74nMAssay Description:Reagents and Materials:Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2023
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Medshine Discovery

US Patent
LigandPNGBDBM600491(US11623923, Example 15)
Affinity DataIC50: 4.05nMAssay Description:Reagents and Materials:Reaction buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSO ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2023
Entry Details
US Patent