BDBM600653 US11629145, Compound 47

SMILES COc1nccc(Oc2n[nH]c3nc(cnc23)N2CCC(C)(N)CC2)c1C#N

InChI Key InChIKey=UBIHTAWLKMOSJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 600653   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
D. E. Shaw Research

US Patent
LigandPNGBDBM600653(US11629145, Compound 47)
Affinity DataIC50: 1.00E+3nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phorphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2023
Entry Details
US Patent